Post Date December, 03 2023
Chronic bacterial prostatitis is basically the same as acute bacterial prostatitis in terms of pathogenic bacteria. The difference in bacterial etiology between the two is that the number of bacteria in the prostate fluid of patients with chronic bacterial prostatitis is relatively small.
Pathogenesis
Like acute bacterial prostatitis, the pathogenic bacteria are gram-negative aerobic bacteria, such as Escherichia coli and Pseudomonas aeruginosa. Some clinicians believe that gram-positive bacteria (such as Staphylococcus, Streptococcus, and Diphtheria like bacteria) can also cause prostatitis, but unlike prostate infections caused by gram-negative bacteria, prostate infections caused by gram-positive bacteria rarely persist or lead to repeated episodes of infection, In addition to the exception of prostatitis caused by enterococci, many authors are skeptical about the chronic prostatitis caused by gram-positive bacteria. Currently, there is evidence that chlamydia and mycoplasma can also cause prostate infection, but it is rare.
Pathogenic characteristics
It may take days or even months to obtain positive results in bacterial culture of prostate fluid, which on the one hand makes a significant difference in clinical practice between chronic bacterial prostatitis and acute bacterial prostatitis; On the other hand, this low bacterial concentration also greatly reduces the effectiveness of antibacterial drugs and the efficiency of the body's autoimmune phagocytosis, thereby increasing the difficulty of diagnosis.
Anatomical characteristics
Anatomically, the glandular ducts of the prostate enter the peripheral zone of the prostate, making it easy for urine to enter the prostate, which inevitably affects the smooth passage of prostate fluid into the urethra. In addition, the edema caused by inflammation in the peripheral zone of the prostate can compress the catheter and further hinder the discharge of prostate fluid. In this situation, the accumulation and blockage of infectious substances lead to the deposition of fibrous tissue in the glandular ducts and the generation of stones, thereby promoting the occurrence and progression of chronic inflammation.
Secretory dysfunction
The secretion dysfunction of the prostate is also considered to be one of the attack mechanisms of bacterial prostatitis, especially chronic bacterial prostatitis. Although the pH of prostate fluid can be acidic or alkaline in normal humans, it is alkaline in patients with chronic bacterial prostatitis. Zinc is present in the prostate fluid of normal humans and is an important component of antibacterial factors, while its level is very low in patients with chronic bacterial prostatitis, which may play an important role in the onset of chronic bacterial prostatitis.
In short, chronic bacterial prostatitis can cause harm to the physical health of men, leading to male friends not being able to work and live normally, affecting the quality of sexual life, and even causing non liquefaction of sperm, decreased sperm activity, leading to infertility. Therefore, once male friends discover bacterial prostatitis, they should promptly go to a regular hospital for diagnosis and treatment.
