Post Date March, 04 2023
Prevention function
Just as the eyelids protect the eyes, the foreskin protects the penis and keeps it soft, moist and sensitive. At the same time, it can also maintain a certain temperature of the penis, adjust the pH balance and have a cleaning effect. The penis itself does not contain sebaceous glands. It relies on the sebum secreted by the foreskin to lubricate and maintain the health of the penis.
Immune protection
The opening of all body organs is the first line of defense for body immune prevention. The gland of the foreskin can secrete anti-bacterial and viral proteins, such as lysozyme, which also exists in tears and mother's milk. Specific epithelial cells, such as Langerhans cells, are components of the immune system and are rich in the outer surface of the foreskin. Plasma cells of the prepuce mucosa can secrete immunoglobulin, which is an antibody to prevent infection.
For many years, we have known that Langerhans cells and dendritic cells play an important role in the immune system of skin and mucosa. In recent years, studies have found that the mucosal immune system is only used to prevent urinary system infection by introducing antigens, that is, sensitization through vaginal mucosa. In theory, the immunoactive prepuce mucosal system can also be used as a way to provide mucosal vaccine.
We have known that Langerhans cells can secrete cytokines. Recently, it was found that without Langerhans cells, squamous epithelial cells can also secrete cytokines and interleukin to stimulate the immune response of T cells. The cytokines released from the prepuce mucosa and skin have not been carefully studied. Weiss, a foreign scholar, did not find Langerhans cells on the mucosal surface of fetal prepuce, but it is easy to be confirmed in the mucosal epithelium of adult prepuce. Langerhans cells were not found on the mucosal surface of the neonatal prepuce, which may be due to the fusion of the prepuce mucosa with the glandular mucosa in the sterile intrauterine environment. Until it grows gradually, the foreskin can retract, and the existence of Langerhans cells can be determined when the mucosa contacts with the antigen.
The role of the diversity of bacteria under the foreskin has not been further studied, and the study of the immune function of the foreskin is only carried out in infants. It was reported that circumcision removed Langerhans cells from the foreskin, presumably reducing the risk of HIV infection. However, this theory has shortcomings. Even after the prepuce is removed, there are still residual glans mucosa and Langerhans cells in the epidermis of the penis. In the United States, the prevalence of circumcision has not prevented the spread of sexually transmitted diseases including HIV. Langerhans cells should therefore be understood as normal mucosal immune cells, rather than a disease requiring resection.
Sexy belt
The foreskin is as sensitive as the fingertips and lips. It contains extremely rich and diverse specific nerve receptors with higher density than any other part of the penis. These special nerve endings can distinguish the sense of movement, subtle temperature changes and the sense of hierarchy of tissue structure.
