Post Date December, 03 2023
According to the doctor, many cases of nephrotic syndrome are accompanied by various diseases during treatment, such as hypertension. At this time, we need to use some antihypertensive drugs to control blood pressure, but if we encounter mild blood pressure and recover after a certain period of time, we can choose not to use the drugs. Let's take a look at the choice of antihypertensive drugs.
(1) Angiotensin converting enzyme inhibitors:
The antihypertensive mechanism of these drugs is mainly achieved by inhibiting the activity of angiotensin converting enzyme, reducing the level of angiotensin II, and relaxing the small arteries. This has a good antihypertensive effect on renal hypertension caused by increased renin secretion due to kidney diseases. In addition, it has a definite effect on delaying the deterioration of renal function, reducing urinary protein, and alleviating glomerulosclerosis, so it is commonly used in clinical practice.
1. captopril: 25 to 50 mg orally once, three times a day.
Benazepril (Lotensin): 10mg orally once a day, which can increase to 40mg daily depending on the condition of the patient.
(2) Calcium antagonists:
Many studies have confirmed that these drugs have the effect of delaying the deterioration of renal function in addition to their antihypertensive effects.
1. Nifedipine: Take 5-10mg orally once, 2-3 times a day.
Amlodipine (Norfloxacin): 5mg once a day, with a maximum dose of 10mg per day, taken orally.
3. β Receptor Blockers:
In addition to reducing blood pressure by reducing cardiac output, these drugs also have the effect of reducing renin, which has a good effect on renin dependent hypertension and does not affect renal blood flow and glomerular filtration rate.
Medoprolol: 50 to 200 mg orally once a day.
2. Carbamate: 50 to 100 mg orally once a day.
(4) "Vasodilatory drugs, such as hydralazine and prazosin, can be selected. The former is typically 200 mg per day, while the latter is typically 6-12 mg per day.".
It can be seen that elevated blood pressure is a stage that patients with nephrotic syndrome must go through. According to doctors, many antihypertensive drugs and nephrotic syndrome treatment drugs can react, potentially causing unpredictable consequences. Therefore, the correct and reasonable selection of antihypertensive drugs is urgent.
