Various etiologies often present irreversible progressive kidney damage, leading to the development of end-stage renal failure. Therefore, early prevention of chronic kidney failure is quite important. The so-called early prevention, also known as "primary prevention", refers to the intervention treatment of relevant factors before the occurrence of chronic kidney failure, including the following aspects:
(1) Actively treat the primary disease. Actively treat various acute and chronic glomerulonephritis, lupus nephritis, purpura nephritis or diseases that may involve the kidney (such as hypertension, diabetes) to prevent the occurrence of chronic renal failure.
(2) Avoiding or eliminating certain risk factors, such as the use of drugs that are toxic to the kidneys, severe infections, dehydration, urinary tract obstruction (such as stones, prostate hypertrophy), trauma, etc., can often exacerbate existing kidney diseases, worsen renal function, and promote renal failure. In fact, regular and high-quality follow-up can reduce or avoid the occurrence of these risk factors, or detect and correct them early.
(3) A reasonable dietary plan with low protein, low phosphorus, and low fat diet has been proven to have a protective effect on renal function in chronic kidney disease in both laboratory and clinical settings. At present, it is emphasized that in order to prevent the occurrence of chronic kidney failure, protein intake should be limited when the blood muscle is drunk at 159.1 μ mol/L.
(4) The application of angiotensin converting enzyme inhibitors can not only control systemic hypertension, but also correct glomerular hyperperfusion and ultrafiltration, and have the effect of delaying the occurrence of renal failure. Commonly used drugs in clinical practice include captopril, lotensin, and lividin.