Post Date December, 03 2023
Many patients with BPH do not take medicine regularly, and there are not a few patients with BPH whose symptoms are not good after taking many drugs. This phenomenon is more common for patients with better economic conditions and medical conditions. So, how should we take the right drugs to treat BPH?
Please pay attention to three problems when taking medicine
Do you know what medicine you are taking
There are many drugs for the treatment of BPH, which can be divided into two categories: one is 5 α- Reductase inhibitors, including finasteride, which is familiar to everyone, as well as Shenitong, Wenlitong, Longbishu, etc. Their main mechanism of action is to reduce the size of the prostate. The other is α- Adrenal receptor blockers. It has many varieties, including Mashani, Gautling, Harle and Zisso. The effect of these drugs is to relieve the resistance of prostate urethra. The main difference is that α The selectivity of receptors is different. These two kinds of drugs perform their respective functions and play different and synergistic roles in treatment. Just choose one of these two kinds of drugs. It is up to the doctor to decide which medicine to take. Some patients are eager for success and wish to get rid of the disease. Repeated medication is not uncommon. If some patients have taken Baoliezhi and Sheniton at the same time; Some patients take both oral and halal. Doing so not only causes waste of drugs, but also aggravates the adverse reactions of drugs. In fact, it is enough to take two drugs at most for the treatment of BPH. If you take too much medicine, you will inevitably have the problem of repeated medication.
Whether the medicine taken is effective
During the medication period, regular reexamination should be carried out to observe the effect of drug treatment. This includes not only the subjective feeling of the patient, such as whether the urination is smooth after taking the medicine, and whether the number of urination at night is reduced compared with that before, but also some objective examinations conducted by doctors, such as the determination of prostate volume, urine flow rate and residual urine by B-ultrasound. At the beginning, the doctor will give the patient 5 at the same time α- Reductase inhibitors and α- Adrenal receptor blocker. If the patient feels that the symptoms have improved, and the objective indicators of dysuria have also begun to improve after the examination, the doctor will generally stop first α- Adrenal receptor blockers. Then, continue to take about 5% α- Reductase inhibitors. During this period, we should also do regular transrectal B-ultrasound examination to understand the changes in prostate volume and whether there is residual urine.
The subjective feelings of patients are important, but the more important thing is to look at the objective indicators. Only when the objective indicators show improvement can the drug treatment be truly effective. After drug treatment, if the indicators of the patient do not improve, the symptoms of dysuria become worse without relief, the number of micturition (especially at night) increases, acute urinary retention occurs, or the residual urine volume is found to be more than 80 ml, the maximum urinary flow rate is less than 10 ml/s, or bladder stones, diverticula, tumors and renal function damage are found, the patient should give up drug treatment and accept surgery.
Whether there are obvious adverse reactions during medication
5 α- Reductase inhibitors generally have no adverse reactions. α- Adrenal receptor blockers have some adverse reactions, the most common of which are headache, dizziness, nasal congestion, orthostatic hypotension, etc. α- Adrenal receptors have different subtypes. The higher the selectivity of drugs to these receptors, the smaller the adverse reactions. In addition, the dosage should be adjusted gradually from a small dose to obtain the maximum effect. It should be taken at night as much as possible to reduce the chance of orthostatic hypotension. During medication, when the patient squats or stands up after sitting for a long time, the movement must be slow to avoid inducing orthostatic hypotension.
