Post Date December, 02 2023
Many patients with chronic prostatitis want to know more about their diseases. One of the issues they are more concerned about is what happens to the prostate after suffering from chronic prostatitis.
From a pathological perspective, changes in the prostate gland after illness vary due to the severity and duration of the disease. Generally speaking, the pathological manifestations of chronic prostatitis are nonspecific, and the inflammatory response is more limited and less obvious than that of acute prostatitis. There are different degrees of plasma cells, macrophages, and regional lymphocyte aggregation in and around the prostatic acini, and there is significant proliferation of fibrous tissue in the glandular lobes. Some patients suffered from obstruction of the glandular duct by pus and exfoliated epithelial cells, resulting in poor drainage and vesicular expansion.
Digital examination of the rectum can touch the prostate gland and show a sense of flexibility. "If prostate fibrosis is severe, the glands can atrophy and extend to the posterior urethra, hardening the bladder neck.". There are also chronic inflammatory changes in the seminal vesicle and ampulla of the vas deferens, with thickening of the wall and proliferation of fibrous tissue around it.
In addition, although soft spot disease belongs to the category of granulomatous prostatitis, it also belongs to the category of chronic prostatitis, because research has confirmed that soft spot disease is caused by infection with gram-negative bacteria, especially related to Escherichia coli. Histologically, there are numerous granulomatous nodules of macrophages and lymphocytes, as well as plasma cells, and a large amount of michael is visible in the cytoplasm of macrophages? Gutman inclusion bodies, round or oval in shape, were positive for PSA and calcium staining.
