Post Date April, 15 2023
The kidney is an important part of the human body. If there is a problem with the kidney, it can have a great impact on the patient. One of them is edema, so why do kidney disease patients have edema? This is a question that patients are very concerned about. Let experts explain it to everyone, hoping to provide some help.
The kidney is the main organ of the human body to expel water and sodium. When the kidney is abnormal, the excretion of water and sodium decreases, resulting in water and sodium retention and edema.
For the cause of edema, medicine generally believes that the kidney is abnormal, leading to the reduction of glomerular filtration rate and retention of water and sodium; The decrease of plasma albumin level leads to the decrease of plasma colloid osmotic pressure; The permeability of capillaries in the whole body changes, allowing body fluid to enter the tissue gap.
According to the different pathogenesis in clinical practice, edema is generally divided into two types: nephrotic edema and nephritic edema.
1. Nephrotic edema: usually occurs in primary glomerulonephritis and various other causes of nephrotic syndrome.
The pathogenesis of this edema is mainly due to the decrease of plasma colloid osmotic pressure: during nephrosis, a large amount of urinary protein causes hypoproteinemia, which causes the decrease of plasma colloid osmotic pressure, increases the filtration of body fluid in capillaries, significantly reduces the body fluid recovered from tissues, and finally forms edema. Decrease of effective blood volume: plasma extravasation reduces the effective blood volume, decreases the secretion of natriuretic hormone, increases the reabsorption of sodium in renal tubules, further increases the retention of water and sodium, and causes edema aggravation.
2. Nephritic edema: mainly seen in acute nephritis, or partial progressive nephritis, chronic nephritis, and other glomerular diseases.
The pathogenesis of this edema is that when acute nephritis occurs, some patients have congestive heart failure due to increased blood volume, hypertension and other reasons, which aggravates the retention of water and sodium; The increase in capillary fluid static pressure causes excessive movement of fluid in capillaries towards tissue gaps, leading to edema.
For edema caused by kidney disease, patients should pay attention to it. During the period of edema, the intake of substances such as sodium and potassium should be reduced, otherwise it can cause very serious consequences. Therefore, patients should treat the edema phenomenon correctly.
