There are several reasons for obstruction of the sperm transport pathway:
(1) Congenital malformation
The common malformation is the absence or atresia of one or both vas deferens, as well as the absence of epididymis. Simple absence of epididymis is relatively rare.
(2) Inflammation
Acute and chronic inflammation of the male reproductive system can cause narrowing or blockage of the sperm transport pathway lumen. Common inflammations include acute and chronic inflammation of the epididymis, vas deferens, seminal vesicles, and prostate gland. In chronic inflammation, special attention should be paid to the specific inflammation caused by Mycobacterium tuberculosis. In addition, one should also be wary of reproductive system inflammation caused by sexually transmitted diseases.
(3) Tumor
Usually benign tumors, such as epididymal adenomatous tumors, leiomyomas and cysts, spermatic cord adenomatous tumors, lipomas, fibromas and cysts, benign prostatic hyperplasia, etc. There are also malignant tumors, such as testicular spermatogonium, embryonic cancer, teratoma, prostate cancer, penis cancer, etc. Some of the above tumors originate from the sperm transport pathway itself, while others originate from the surrounding organs of the sperm transport pathway, which can cause blockage and external pressure in the pathway lumen, affecting the passage of sperm.
(4) Trauma
Trauma to the scrotum or perineum can damage the epididymis and vas deferens, causing partial or complete rupture of the lumen, and even healing scars that can affect sperm passage.
(5) Other symptoms
Giant inguinal hernia and testicular torsion can also cause obstruction of the sperm transport pathway.
(Intern Editor: Cai Junyi)