Many people believe that hypertension and kidney disease are not related, but in fact, hypertension and kidney disease are closely related and often "inseparable".
What is the relationship between kidney disease and hypertension
We all know that the kidneys excrete waste from the body by producing urine, which is produced by the pressure of blood in the kidneys. Therefore, the kidney is the area with the highest blood pressure in the body, and it is also the organ that is most vulnerable to damage when blood pressure is high.
Research proof
Hypertension can cause hypertensive nephropathy and renal artery stenosis, which has become an important cause of uremia. Most patients with hypertensive nephropathy do not have obvious discomfort and can only be diagnosed through some special examinations, so early treatment is often overlooked and the best time for treatment is missed.
In addition, when blood pressure is high, the elevation of microalbumin in urine not only represents renal lesions, but also indicates systemic vascular lesions, which has a good predictive effect on heart disease and stroke.
It is often said that "a thousand mile levee will collapse in an ant nest". Although micro albuminuria seems insignificant at the early stage of hypertension with diabetes nephropathy, it is like a small ant nest on a thousand mile levee. If it is allowed to develop, the consequences will be unimaginable, which can lead to kidney failure and require dialysis or kidney transplantation to maintain life. For the treatment of hypertension complicated with diabetes nephropathy at the early stage, as long as patients take appropriate antihypertensive drugs, such as angiotensin II receptor antagonist Ambovey, it is possible to reduce or even eliminate microalbumin in urine, "cut off" the natural course from early nephropathy to late nephropathy, thus greatly reducing the risk of developing to late nephropathy.
When there is a lesion in the kidneys or renal blood vessels, the secretion of renin will suddenly increase, causing spasms in the small arteries throughout the body, leading to increased resistance to small arteries and hypertension. The incidence, duration, and degree of elevated blood pressure of this type of hypertension are related to the degree of renal damage and pathological changes.
When suffering from acute nephritis
The duration of elevated blood pressure is relatively short (usually 2-3 weeks), and blood pressure can return to normal.
When suffering from chronic nephritis
The increase in blood pressure lasts for a long time and is relatively constant, making it difficult to recover. When kidney disease occurs, the synthesis and secretion of prostaglandins decrease, while the secretion of renin is extremely increased. The imbalance between the two leads to an increase in blood pressure.
Kidney diseases, such as chronic nephritis and pyelonephritis, are the most common secondary causes of hypertension.
Whether it is hypertension caused by kidney disease or hypertension caused by kidney disease, there are special requirements for blood pressure control. Patients must choose drugs that can effectively reduce blood pressure and protect the kidneys. For some special situations, such as renal artery stenosis and decreased renal function, some antihypertensive drugs are not suitable for use or need to be reduced in dosage; Patients with high levels of proteinuria have higher requirements for blood pressure reduction, and blood pressure must be controlled below 17.3/10.7 kPa (130/80 mmHg).