Post Date November, 16 2024
The human body has a complete natural process from infection with AIDS virus to onset, which is clinically divided into four stages: acute infection period, incubation period, pre AIDS period, and typical AIDS period. After the symptoms of AIDS acute infection period appear, it will continue to be in the Asymptomatic period, that is, the incubation period of AIDS. When the cellular immune function is low, the disease starts. Generally speaking, the incubation period of AIDS can last for 2-10 years, or more than 15 years. Next, experts introduce AIDS latency symptoms. Experts introduce AIDS latency symptoms 1. Skin damage, skin and mucous membrane are one of the main parts of AIDS invasion, and many AIDS patients take skin damage as the first symptom. There are many clinical manifestations, such as rash, systemic itching, Genital wart, contact condyloma, Hives, etc. 1. Infectious skin and mucosal lesions. 64% of AIDS patients are accompanied by Skin infection. It is believed that the occurrence of Skin infection is mainly due to the reduction of Th cells and skin Langerhans cells, which reduces the immune function of skin cells, causes infection, and is difficult to treat and easy to relapse. Among various infections, the most significant ones are severe Herpes simplex, Shingles, chronic acne like Folliculitis and chronic mucocutaneous candidiasis. 2. Non infectious skin and mucosal lesions. Some other skin lesions may occur in AIDS patients. The most common ones are Seborrhoeic dermatitis, herpetic or measles like pruritic rash, annular processes like circular Granuloma, Folliculitis, yellow nail syndrome, vasculitis, cluster alopecia, blood spots, eosinophilic pustular Folliculitis, multiple eyelashes, etc. 3. Tumor skin manifestations include KS, lymphoma, Cutaneous squamous-cell carcinoma, Basal-cell carcinoma, etc. KS sarcoma is the most common initial manifestation in AIDS patients. The sarcoma is single or disseminated. The color changes from light brown to dark purple. Its shape can be from plaque to tumor node, or it can be follicular, Shingles like or linear. Compared with KS sarcoma in non AIDS patients, KS sarcoma is more atypical. 2、 When Lymphadenopathy is in the incubation period of AIDS, the incidence of Lymphadenopathy is 55%~100%. When patients in high-risk groups have Lymphadenopathy and cannot be explained by other reasons, it is likely to be related to HIV infection. Although swollen lymph nodes are systemic, they are more common in the posterior cervical, submaxillary, or axillary lymph nodes. The enlarged lymph nodes do not fuse, are hard and occasionally tender, with no surface skin changes. The degree of Lymphadenopathy is related to the titer of AIDS antibody in serum. In addition, AIDS is accompanied by lymphoma, including Burkitts lymphoma, immunoblastic lymphoma and Hodgkin's disease, and Lymphadenopathy can also occur. 3、 Central nervous system symptoms and neurological disorders have been recognized as the common cause of morbidity and mortality in children and adults with AIDS. 20%~40% of AIDS patients with latent symptoms of AIDS have neurological diseases. Introduction to several stages of AIDS (I) Acute phase: it usually occurs about 2-4 weeks after the initial HIV infection. The main clinical manifestations are fever, sore throat, night sweat, nausea, vomiting, diarrhea, rash, Arthralgia, Lymphadenopathy and nervous system symptoms. Most patients have mild clinical symptoms that persist for 1-3 weeks before relieving. During this period, HIV-RNA and p24 antigen can be detected in the blood, while HIV antibodies do not appear until a few weeks after infection. The CD4+T lymphocyte count transiently decreases, and the CD4/CD8 ratio can be inverted. 2） The Asymptomatic phase can enter this phase from the acute phase, or enter this phase directly without obvious acute symptoms. The duration of this period is generally 6-8 years. But there are also those who have made rapid progress and those who have not made progress for a long time. The length of this period is related to various factors such as the number, type, route of infection, and immune status of the infected virus. （3） AIDS is the final stage after HIV infection. The patient's CD4+T lymphocyte count significantly decreased, with more
