After the first miscarriage, women need to undergo a detailed examination to determine the root cause of the miscarriage; Or earlier, when planning for pregnancy, comprehensive pre pregnancy examinations should be done, not only for women, but also for men, including routine blood tests and sperm quality testing. In modern life, there are more and more factors that can harm male sperm. We should pay more attention to sperm health issues and prepare in advance for healthy pregnancy preparation and safe pregnancy.
Chromosome abnormalities
Chromosomes record the basic information necessary for fetal development, and once it goes wrong, it can easily lead to miscarriage. Chromosome problems are not uncommon, and according to statistics, about 20% to 55% of early miscarriages are caused by chromosomal abnormalities in the embryo. Chromosome problems are a clear cause of many women's miscarriage and embryo arrest, so it is often necessary to check chromosomes when seeking medical attention at reproductive centers.
【 Response 】: If it is indeed a chromosomal problem that causes recurrent miscarriage, it is usually done through PGD (pre embryo transfer genetic diagnosis), commonly known as the "third generation in vitro fertilization technology" to assist in pregnancy. This method can filter out embryos with chromosomal problems.
The semen is infected
Chlamydia trachomatis infection and ureaplasma urealyticum infection are important reasons for recurrent abortion. These tiny pathogens can attach to the surface of sperm, and then affect the health of zygote or embryos, leading to abortion.
[Countermeasures]: Targeted treatment and elimination of Chlamydia trachomatis and ureaplasma urealyticum can reduce the risk of abortion and fetal suspension.
Sperm looks unattractive
The problem of sperm appearance here refers to the problem of sperm morphology. Common abnormalities such as abnormal acrosome in the sperm head can prevent sperm from penetrating the egg, leading to loss of fertilization ability and infertility or miscarriage. Another example is the abnormal chromatin of sperm, which is mostly manifested as abnormal head morphology (such as megacephalic sperm). The likelihood of miscarriage increases significantly when these types of sperm combine with the egg.
【 Response Method 】: For patients with severe abnormal sperm syndrome, if drug treatment is ineffective, ICSI (egg count) needs to be used
Intraplasmic sperm injection technology, also known as the "second generation in vitro fertilization technology" for assisted pregnancy, can select healthy sperm with normal appearance.
Poor sperm motility
Previously, it was believed that sperm had poor motility and could not swim into the cervix, uterus, or fallopian tubes on their own to conceive when they met the egg. However, research has shown that sperm with poor motility may also cause the female to conceive, and the probability of miscarriage after conception is significantly higher than that of the normal population.
【 Response 】: Cooperate with a doctor to find the cause of poor sperm motility (asthenozoospermia) and treat it. Common diseases include varicocele, epididymitis, seminal vesiculitis, etc.
High sperm DNA fragmentation rate
The high rate of sperm DNA fragments indicates that the integrity of genetic material in sperm is poor, and the integrity of genetic material in sperm is extremely important for fertilization and the development of zygote. Research shows that populations with a sperm DNA fragment rate higher than 30% have a significantly higher probability of infertility or early miscarriage.
【 Response method 】: For patients with high sperm DNA fragmentation rate, most of them are currently treated with vitamin based antioxidant drugs, and the situation of most patients will improve. In some cases, repeated treatment is ineffective, and sperm can be removed through testicular puncture, followed by in vitro fertilization, which may also lead to successful pregnancy.
Bad lifestyle habits
Excluding the female factor, the male did not show any obvious abnormalities in various examinations, but there is still a possibility of recurrent miscarriage, which is usually related to adverse lifestyle factors such as age, environment, smoking, and alcohol consumption.
【 Response 】: Within the optimal reproductive age (preferably before the age of 35), stay away from smoking and alcohol, avoid soaking in hot springs and saunas, wear less tight clothes and pants, do not abuse chemical drugs, and develop good lifestyle habits.