Post Date December, 02 2023
If the father's surface antigen and e antigen are both positive, the infection rate of the baby born to him can reach more than 80%; When the father's e antibody is positive, the infection probability of his offspring is about 20%. After the fetus is infected with hepatitis B virus, it can not only become a patient or carrier of hepatitis B virus, but also affect the normal growth and development of the fetus, which can cause low birth weight infants, congenital diseases or malformations, abortion, stillbirth, etc. Therefore, we should pay enough attention to the father to child transmission of hepatitis B virus.
If the spouse is healthy, and the person infected with HBV is HbsAg positive, or is "small three positive" or "small two positive", the HBV-DNA is negative and has no clinical symptoms, the liver function is normal, and the B-ultrasound of liver and spleen is normal, it indicates that HBV has not replicated in the body and is extremely infectious.
Since direct father to child transmission occurs in the germ cell stage, the most effective way to block father to child transmission of hepatitis B is pre pregnancy intervention.
1、 Newly married couples should have hepatitis B examination before marriage, and both men and women should be actively treated no matter whether they have hepatitis B. It is best to marry and have children after the disease is cured without infection or stable. If the mother can successfully immunize hepatitis B vaccine until the antibody appears before pregnancy, this is the best pregnancy period, which can effectively protect pregnant women and newborns, thus effectively reducing the possibility of hepatitis B virus infection.
2、 The way to prevent father to child transmission is to timely vaccinate the newborn with hepatitis B vaccine according to the planned immunization measures, so that the child can be vaccinated with hepatitis B vaccine after birth. There are also some useful methods to choose from: during pregnancy, 200IU of hepatitis B immunoglobulin is injected intramuscularly every 4 weeks since the birth inspection at the 20th week of pregnancy, which can effectively neutralize the hepatitis B virus in the pregnant women's blood, and its purpose is to further strengthen the pregnant women's ability to resist the husband's hepatitis B virus infection, while reducing the chance of hepatitis B virus father mother infant transmission. In addition to the prescribed hepatitis B vaccine, the newborn born to a father and (or) mother who is a carrier of hepatitis B virus should also be injected with highly effective hepatitis B immunoglobulin within 24 hours and one month after birth, 100 IU at a time, in order to better protect the newborn.
Therefore, we remind that in cases where only the father of the couple has evidence of hepatitis B virus infection, education should be strengthened to make them have a deeper understanding of the spread of hepatitis B virus, so as to better cooperate with doctors to use reasonable methods to prevent pregnant women and their children from being infected by hepatitis B virus of the father.
