Post Date December, 03 2023
There are many reasons that directly cause pediatric kidney disease, but the main cause of pediatric kidney disease is that when children catch a cold, the immune cells in the human body will swallow the invading bacteria and viruses, generate an antibody, and then die, achieving the function of eliminating bacteria to ensure that the human body is not affected. Children, due to their weak constitution, have fewer immune cells in their body than normal people, so their immune function is not strong enough. Therefore, sometimes the immune cells not only do not swallow the bacteria in the children's body, but also temporarily contain the bacteria. This causes the bacteria antibodies in the children's body to combine with the bacteria themselves, forming an immune complex that circulates with the blood and deposits into the basement membrane of the glomeruli when it reaches the children's kidneys, This can cause damage to the kidneys of children, causing a large amount of protein to be lost in their urine. Ultimately, it leads to the occurrence of kidney disease in children.
Children often have the following symptoms after kidney disease occurs
1. Edema
At the beginning of pediatric kidney disease, there will be varying degrees of swelling in the lower limbs, head, face, and trunk. Especially in areas with loose tissue, such as the eyelids, the boy's scrotum can become swollen like a light bulb, and there is also fluid accumulation in the visceral serous cavity, such as pleural effusion and ascites. People with severe swelling have thin and transparent skin, and slight skin damage can cause water seepage
2. Striae appear on the body
After suffering from kidney disease, some children may develop skin white or purple lines similar to those of pregnant women on the inner thighs and upper arms, abdomen, and chest.
3. Urinary abnormalities
Children with kidney disease will suddenly have nocturnal urine frequency, dark urine color, decreased urine volume, and increased foam in urine.
Due to the lack of pathological awareness in children, even if abnormal urine is detected, they will not pay attention. Therefore, parents should pay more attention to the children's daily behavior in their daily lives.
4. Decreased immunity in children
When a child's body undergoes pathological changes, their immune system may decrease, leading to loss of appetite, pale complexion, poor protein nutrition, dry and withered hair, keratinized hair follicles, dry skin, white stripes on fingernails, delayed development, anemia, and susceptibility to infection.
5. Urinary protein
Protein is mainly caused by damage to inherent kidney cells, ischemia hypoxia necrosis, increased permeability of glomerular filtration membrane, and protein leakage from it. Hormones can only control surface symptoms and temporarily control protein leakage, but they cannot repair damaged kidneys. They are prone to recurrence when encountering colds, infections, etc.
6. Hypertension
Blood pressure can increase to varying degrees, often with episodic or persistent hypertension and hematuria
7. Hypoalbuminemia
Serum complement levels can be reduced, leading to varying degrees of azotemia
8. Hyperlipidemia:
Plasma cholesterol, triglycerides, low density and extremely low density lipoprotein can all be clearly increased.
Although pediatric kidney disease has many symptoms, it has different symptoms at different stages of onset, and the severity of some symptoms varies among different stages of the disease.
Generally speaking, in the early stages of pediatric kidney disease, the symptoms of kidney disease are not obvious, and some symptoms are easily confused with other diseases. Therefore, it is necessary to pay more attention to the early symptoms of pediatric kidney disease. Once symptoms are found, it is necessary to go to the hospital for examination as soon as possible to avoid confusion with other diseases, causing misdiagnosis, or delaying treatment time.
