Dead sperm syndrome refers to a decrease in sperm survival rate, with over 40% dead sperm. This disease is one of the causes of male infertility. If the semen test shows that dead sperm account for over 40%, it can be diagnosed as this disease. An increase in dead sperm caused by improper examination methods or failure to follow normal regulations, or extremely weak or inactive sperm activity that is not true dead sperm, does not belong to this disease.
Six major causes of azoospermia
1. The lack of fructose, which is essential for the survival of certain sperm in semen, is an extremely important substance to ensure sperm survival and activity. For example, when there is inflammation in the vas deferens, the fructose content in normal seminal vesicle fluid will decrease, affecting the survival of certain sperm.
2. The normal pH value of semen changes from 7.2 to 8.9, which is slightly alkaline. The pH value of semen in azoospermia is lower than 7.2, and the acidity of semen is relatively high, which may be a factor causing sperm death. The decrease in semen pH value is related to inflammatory lesions of the reproductive organs, as bacterial metabolites can cause a decrease in semen pH value.
3. When there is inflammation in the reproductive organs due to insufficient oxygen supply, congestion, edema, blood stasis, and slow blood circulation can occur, resulting in a decrease in oxygen provided by the blood. Sperm can die due to hypoxia.
4. The normal zinc content in semen should be 80-25? G/mL, and when prostatitis occurs, it can reduce the zinc content in semen to 50? Below g/mL, sperm are prone to death.
5. Physical factors such as high temperature and radiation can reduce the survival rate of sperm and lead to sperm death due to local high temperature or exposure to high-dose radiation, or long-term exposure to radiation.
6. Drug factors can cause azoospermia by taking drugs that can damage sperm, such as Tripterygium wilfordii and cyclophosphamide.