Post Date December, 02 2023
Symptoms of venereal disease I. Acute gonorrhea: primary urethritis
1. Latency: The incubation period of acute gonorrhea is very short, usually 2 to 5 days after sexual contact, and the incubation period of very few patients can be as long as 10 days. There are three stages after gonococcal invasion into the male urethra: ① invasion stage: it takes 36 hours after gonococcal invasion to penetrate into the superficial layer of the mucosa and begin to reproduce and grow. ② Development stage: complete a life cycle in about 36 hours. ③ Detoxification stage: after the life cycle, some gonococci die and excrete endotoxins, thus causing the body tissue to react to the toxin, and then clinical symptoms appear.
The factors affecting the length of incubation period include: the extensive effect of antibiotics; Physical weakness, decreased resistance, alcoholism, excessive sexual life, etc. The incubation period can be shortened for those who are addicted to alcohol and color, and prolonged for those who use antibiotics.
2. Conscious symptom
1. Urodynia is often the early symptom of the disease. There is burning sensation, tingling or burning pain in the front of the urethra, and the pain is significantly increased during urination, even radiating to the lower abdomen or spine. "Painful erection" can occur in patients with nocturnal pain.
2. After 12~24 hours, the pain of urethral lipstick swelling and purulent discharge slightly relieved, and began to discharge thin mucus-like secretions in a large amount. After 12~24 hours, a large amount of purulent secretions were discharged, and 20~50ml of pus could be discharged in 24 hours. After 2 to 3 days, the amount of pus decreased and became thick, and the color changed from white to yellow-white or yellow-brown. After 3 to 4 days, the pus was less and thick. In the morning, the pus gathered at the urethral orifice, forming a pus membrane, called "living mouth". The pain was reduced, the urethral orifice was red and swollen, showing an everted shape, and the inner leaf of the foreskin was also red and swollen, and could develop into prepuceitis, incarcerated phimosis, etc.
3. Frequent urination is similar to common urinary tract infection, which causes contraction of urethral sphincter due to inflammation. Frequent urination is most common at night. In addition, "terminal hematuria" often occurs because the inflammation affects the small blood vessels in the mucosa. Sometimes there may be blood essence.
4. Falling swelling pain clinically appears, which indicates that the disease has invaded the posterior urethra, prostate and seminal vesicle.
5. Systemic symptoms Individual patients will also have systemic symptoms, such as fever and temperature of about 38 ℃, general tiredness, weakness, discomfort, anorexia, and even nausea and vomiting.
3. Physical examination: the urethral orifice and entrance fossa are red, swollen, congested and edematous, sometimes with small or superficial abscess, erosion or small ulcer. In severe cases, the urethra mucosa is everted, the red swelling affects the whole head, and the prepuce is everted, the prepuce cannot be turned up, and the pus can flow out when the urethra is compressed. The inguinal lymph nodes on both sides can also be involved, causing redness, cramp, suppuration, and obvious tenderness, which will decrease with the reduction of urethritis. The inflammation of lymph nodes will also disappear 2 to 3 days after the disappearance of inflammation.
4. Evolution of the course of disease: The symptoms are the most severe in the first week. If they are not treated or not treated timely and thoroughly, the symptoms will gradually reduce after about 2 to 3 weeks, the secretion of the urethra will decrease, the tissue swelling will also subside, and the symptoms will completely disappear after one month. However, gonorrhea has invaded the deep gland at this time, and even lurked in the scar tissue to grow slowly, developing into chronic gonorrhea, and later urethral stricture may occur.
(Intern editor: Cai Junyi)
