Post Date December, 02 2023
In the early stages of renal failure, there are often no clinical symptoms except for an increase in blood creatinine, which only manifests as symptoms of the underlying disease. When the condition progresses to the point where the residual nephron cannot adjust to meet the minimum requirements of the body, the symptoms of renal failure gradually manifest. In the initial stage of renal failure, there are usually no symptoms to warn patients that their kidneys are no longer functioning properly. This is also why frequent urine and blood tests are very important. Sometimes even if the patient feels good about themselves, the results of their health check ups may show some signs of kidney disease. However, when the renal function is close to complete loss, the patient's physical changes and symptoms of the disease will become apparent.
So what is willing to cause kidney failure? Director Zhang, a nephrologist at Shijiazhuang Yanzhao Hospital, gave the following explanation: The potential risk factors for chronic renal failure mainly manifest in the following three aspects:
1. Hemodynamic changes in the human body: Insufficient blood perfusion, such as in the event of shock, congestive heart failure, heart disease, thrombus (DIC), heatstroke, excessive vasoconstriction, and relaxation diseases, results in a relatively insufficient amount of blood passing through the kidneys, resulting in a relative decrease in the metabolic rate of waste, leading to the accumulation of nitrogen-containing waste and increasing the burden on the kidneys, leading to renal failure.
2. Harm of toxic substances: Many drugs in daily life can cause significant damage to the kidneys, such as certain antibiotics, chemotherapy drugs, non steroidal analgesics, X-ray imaging agents, alcohol, heavy metal poisoning (lead, mercury, arsenic, thallium), or venom from insects and snakes. These drugs can cause varying degrees of toxic reactions to the kidneys, leading to renal dysfunction and ultimately kidney failure.
3. Diseases of the body itself: leptospira infection, autoimmune nephritis, liver failure, bacterial endocarditis, pyelonephritis, and lymphosarcoma. When these diseases exist in the body itself, it is often easy to cause kidney damage, which also becomes the main cause of kidney failure.
