In summary, the cause of renal failure is nothing more than insufficient blood co drinking in the kidneys, or a series of pathological changes in the kidneys. However, what is the typical cause of renal failure? This is what we must know now. The main cause is renal tubular necrosis. So, what is the cause of renal tubular necrosis? Now, we are slowly pursuing the cause of renal failure, that is, glomerular necrosis. The causes are diverse, and we will work together.
The etiology of renal failure is as follows: Kidney poisoning is caused by substances that are toxic to the kidneys, such as sulfonamide, carbon tetrachloride, mercury, bismuth, and dichlorophenamide in drugs; Polymyxin in antibiotics, vancomycin, kanamycin, gentamicin, cephalosporin I, cephalosporin II, neomycin, amphotericin B, iodine contrast agents, methoxyflurane anesthetics, etc; Biological toxins such as snake venom, bee venom, fish mushroom, cantharidin, etc. can cause acute renal tubular necrosis under certain conditions.
The second cause of renal failure: Severe renal ischemia, such as severe trauma, extensive burns, major surgery, massive blood loss, obstetric hemorrhage, severe infection, sepsis, dehydration, and electrolyte imbalance, especially in patients with shock, can easily lead to acute tubular necrosis.
The third cause of renal failure is hemoglobin released from intravascular hemolysis (such as black urine fever, hemolysis caused by primaquine, fava bean disease, blood group incompatible transfusion, arsenic oxide poisoning, etc.), as well as myoglobin during massive muscle trauma (such as crush injury, muscle inflammation). Through renal excretion, it can damage renal tubules and cause acute renal tubular necrosis.
"Now, we understand that the cause of renal failure is essentially necrosis of the renal tubules. Therefore, if we want to truly cure our renal failure, we must repair our renal failure. Only in this way can we fundamentally eliminate necrosis of the renal tubules, and if we do so, we must repair our renal tubules from now on.".