Post Date April, 15 2023
There are several methods for treating prostate cancer, including endocrine therapy. However, many people do not know what endocrine therapy is for prostate cancer. Below, experts will introduce endocrine therapy for prostate cancer.
Prostate cancer has a significant hormone dependence. Lowering male hormone levels can atrophy the prostate epithelium in adults and significantly alleviate symptoms of prostate cancer, making it widely used in the treatment of prostate cancer. Endocrine therapy for prostate cancer includes testicular resection, the use of estrogen, antiandrogens, adrenocortical hormones, adrenalectomy, and pituitary suppression.
1. Estrogen therapy: Estrogen can directly inhibit the production of testicular steroid hormones, and affect the metabolism of prostate cells, causing gland atrophy. The main adverse reactions are breast development, nausea, vomiting, etc. High dose use can cause cardiovascular complications.
2. Anti androgen treatment: The main drugs include estradiol phosphate nitrogen mustard, aminophenidate, methylmedroxyprogesterone, etc., which should be taken under the guidance of a doctor.
3. Adrenocortical hormone therapy: This endocrine therapy for prostate cancer can inhibit the production of androgens by the adrenal glands, thereby treating prostate cancer.
4. Testectomy.
5. Adrenalectomy: This endocrine treatment for prostate cancer. In theory, adrenalectomy can significantly reduce androgen production and atrophy tumor cells. However, adrenalectomy is a very dangerous surgery that is rarely used clinically.
(Intern Editor: Cai Junyi)
