The changing weather, with temperatures noticeably fluctuating, can easily cause children to catch a cold. According to relevant experts, colds can induce pediatric nephrotic syndrome. Kidney disease is often induced by upper respiratory tract infections. There are many cases of pediatric nephrotic syndrome caused by upper respiratory tract infections during early spring or seasonal changes. This is because the weather is suddenly cool and hot, and children are prone to respiratory infections, such as colds, tonsillitis, acute pharyngitis, etc. If the infection is not effectively controlled in a timely manner, it may trigger nephrotic syndrome after 1-4 weeks.
There are many causes of pediatric nephrotic syndrome. When catching a cold, immune cells in the human body will swallow invading bacteria and viruses, form an antibody, and then die, achieving the function of eliminating bacteria to ensure that the human body is not affected. Children, due to their weak physique, have fewer immune cells in their bodies than normal people, and their immune function is not strong. Therefore, sometimes immune cells not only do not swallow the bacteria, but also temporarily contain them. Antibodies to the bacteria in the body combine with the bacteria themselves to form an immune complex. As the blood circulates, when they reach the kidneys, they will deposit on the basement membrane of the glomeruli, causing damage to the kidneys and causing a large amount of protein loss, Ultimately, it leads to nephrotic syndrome.
Kidney disease experts explained a detailed answer: Children often have swollen eyelids within 4 weeks after catching a cold. Nephrotic syndrome can occur at any age, but it is more common in young people and children. Minimally degenerative nephrotic syndrome is more common in children aged 2 to 6 years old, with more boys than girls, making it prone to recurrence and extension, with a long course of disease. It usually occurs 1-4 weeks after infection with the pathogen. Generally speaking, pediatric nephrotic syndrome has pre infection symptoms, characterized by three highs and one low, namely high edema, high proteinuria, hypercholesterolemia, and hypoproteinemia. Within 1 to 4 weeks after catching a cold, the child's lower limbs, head, face, and trunk can have swelling, especially in areas with loose tissue. The most obvious and earliest appearance is the eyelids. Severe cases of swelling have thin and transparent skin, with pleural and abdominal fluids. If the skin is slightly damaged, it will seep. Some children may have skin white or purple lines similar to those of pregnant women on the inner thighs and upper arms, abdomen, and chest; Urinary output has significantly decreased, and there are 3-4 plus signs of proteinuria in the urine routine. The loss of a large amount of protein from the urine has become the main cause of hypoproteinemia.